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Berkatens Brand names, Berkatens Analogs

Berkatens Brand Names Mixture

  • Tarka (trandolapril + verapamil hydrochloride)

Berkatens Chemical_Formula


Berkatens RX_link

Berkatens fda sheet

Berkatens FDA

Berkatens msds (material safety sheet)

Berkatens Synthesis Reference

Dengel, U.S. Pat. 3,261,859 (1966)

Berkatens Molecular Weight

454.602 g/mol

Berkatens Melting Point

< 25 oC

Berkatens H2O Solubility

4.47 mg/L

Berkatens State


Berkatens LogP


Berkatens Dosage Forms

Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)

Berkatens Indication

For the treatment of hypertension and angina.

Berkatens Pharmacology

Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.

Berkatens Absorption


Berkatens side effects and Toxicity

LD50=8 mg/kg (i.v. in mice)

Berkatens Patient Information

Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses may need some adjustment, make sure to have your condition monitored regularly.

Berkatens Organisms Affected

Humans and other mammals