Cordilox
Brand names,
Cordilox
Analogs
Cordilox
Brand Names Mixture
- Tarka (trandolapril + verapamil hydrochloride)
Cordilox
Chemical_Formula
C27H38N2O4
Cordilox
RX_link
http://www.rxlist.com/cgi/generic/verapsr.htm
Cordilox
fda sheet
Cordilox
msds (material safety sheet)
Cordilox
Synthesis Reference
Dengel, U.S. Pat. 3,261,859 (1966)
Cordilox
Molecular Weight
454.602 g/mol
Cordilox
Melting Point
< 25 oC
Cordilox
H2O Solubility
4.47 mg/L
Cordilox
State
Liquid
Cordilox
LogP
5.931
Cordilox
Dosage Forms
Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)
Cordilox
Indication
For the treatment of hypertension and angina.
Cordilox
Pharmacology
Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.
Cordilox
Absorption
90%
Cordilox
side effects and Toxicity
LD50=8 mg/kg (i.v. in mice)
Cordilox
Patient Information
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Cordilox
Organisms Affected
Humans and other mammals