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Dignover Brand names, Dignover Analogs

Dignover Brand Names Mixture

  • Tarka (trandolapril + verapamil hydrochloride)

Dignover Chemical_Formula


Dignover RX_link


Dignover fda sheet

Dignover FDA

Dignover msds (material safety sheet)

Dignover Synthesis Reference

Dengel, U.S. Pat. 3,261,859 (1966)

Dignover Molecular Weight

454.602 g/mol

Dignover Melting Point

< 25 oC

Dignover H2O Solubility

4.47 mg/L

Dignover State


Dignover LogP


Dignover Dosage Forms

Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)

Dignover Indication

For the treatment of hypertension and angina.

Dignover Pharmacology

Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.

Dignover Absorption


Dignover side effects and Toxicity

LD50=8 mg/kg (i.v. in mice)

Dignover Patient Information

Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses may need some adjustment, make sure to have your condition monitored regularly.

Dignover Organisms Affected

Humans and other mammals