Veraptin
Brand names,
Veraptin
Analogs
Veraptin
Brand Names Mixture
- Tarka (trandolapril + verapamil hydrochloride)
Veraptin
Chemical_Formula
C27H38N2O4
Veraptin
RX_link
http://www.rxlist.com/cgi/generic/verapsr.htm
Veraptin
fda sheet
Veraptin
msds (material safety sheet)
Veraptin
Synthesis Reference
Dengel, U.S. Pat. 3,261,859 (1966)
Veraptin
Molecular Weight
454.602 g/mol
Veraptin
Melting Point
< 25 oC
Veraptin
H2O Solubility
4.47 mg/L
Veraptin
State
Liquid
Veraptin
LogP
5.931
Veraptin
Dosage Forms
Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)
Veraptin
Indication
For the treatment of hypertension and angina.
Veraptin
Pharmacology
Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.
Veraptin
Absorption
90%
Veraptin
side effects and Toxicity
LD50=8 mg/kg (i.v. in mice)
Veraptin
Patient Information
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Veraptin
Organisms Affected
Humans and other mammals