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Isoptin Brand names, Isoptin Analogs

Isoptin Brand Names Mixture

  • Tarka (trandolapril + verapamil hydrochloride)

Isoptin Chemical_Formula


Isoptin RX_link

Isoptin fda sheet

Isoptin FDA

Isoptin msds (material safety sheet)

Isoptin Synthesis Reference

Dengel, U.S. Pat. 3,261,859 (1966)

Isoptin Molecular Weight

454.602 g/mol

Isoptin Melting Point

< 25 oC

Isoptin H2O Solubility

4.47 mg/L

Isoptin State


Isoptin LogP


Isoptin Dosage Forms

Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)

Isoptin Indication

For the treatment of hypertension and angina.

Isoptin Pharmacology

Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.

Isoptin Absorption


Isoptin side effects and Toxicity

LD50=8 mg/kg (i.v. in mice)

Isoptin Patient Information

Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses may need some adjustment, make sure to have your condition monitored regularly.

Isoptin Organisms Affected

Humans and other mammals