Geangin
Brand names,
Geangin
Analogs
Geangin
Brand Names Mixture
- Tarka (trandolapril + verapamil hydrochloride)
Geangin
Chemical_Formula
C27H38N2O4
Geangin
RX_link
http://www.rxlist.com/cgi/generic/verapsr.htm
Geangin
fda sheet
Geangin
msds (material safety sheet)
Geangin
Synthesis Reference
Dengel, U.S. Pat. 3,261,859 (1966)
Geangin
Molecular Weight
454.602 g/mol
Geangin
Melting Point
< 25 oC
Geangin
H2O Solubility
4.47 mg/L
Geangin
State
Liquid
Geangin
LogP
5.931
Geangin
Dosage Forms
Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)
Geangin
Indication
For the treatment of hypertension and angina.
Geangin
Pharmacology
Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.
Geangin
Absorption
90%
Geangin
side effects and Toxicity
LD50=8 mg/kg (i.v. in mice)
Geangin
Patient Information
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Geangin
Organisms Affected
Humans and other mammals