Categorie
Verapamil
Les marques,
Verapamil
Analogs
Verapamil
Les marques melange
Tarka (trandolapril + verapamil hydrochloride)
Verapamil
Formule chimique
C27H38N2O4
Verapamil
RX lien
http://www.rxlist.com/cgi/generic/verapsr.htm
Verapamil
FDA fiche
Verapamil
msds (fiche de securite des materiaux)
Verapamil
Synthese de reference
Dengel, le brevet américain. 3,261,859 (1966)
Verapamil
Poids moleculaire
454.602 g/mol
Verapamil
Point de fusion
< 25 oC
Verapamil
H2O Solubilite
4,47 mg / L
Verapamil
Etat
Liquid
Verapamil
LogP
5.931
Verapamil
Formes pharmaceutiques
Capsule (libération prolongée); liquide; Solution; Tablet; Tablet (libération prolongée)
Verapamil
Indication
Pour le traitement de l'hypertension et l'angine.
Verapamil
Pharmacologie
Vérapamil, un anti-arythmique de classe IV agent, est utilisé comme un blocage des canaux calciques (BCC) agent pour le traitement de l'angine, l'hypertension, et pour tachyarythmies supraventriculaires.
Verapamil
Absorption
90%
Verapamil
Toxicite
DL50 = 8 mg / kg (iv chez la souris)
Verapamil
Information pour les patients
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Verapamil
Organismes affectes
Les humains et autres mammifères