Categorie
Isoptin SR
Les marques,
Isoptin SR
Analogs
Isoptin SR
Les marques melange
Tarka (trandolapril + verapamil hydrochloride)
Isoptin SR
Formule chimique
C27H38N2O4
Isoptin SR
RX lien
http://www.rxlist.com/cgi/generic/verapsr.htm
Isoptin SR
FDA fiche
Isoptin SR
msds (fiche de securite des materiaux)
Isoptin SR
Synthese de reference
Dengel, le brevet américain. 3,261,859 (1966)
Isoptin SR
Poids moleculaire
454.602 g/mol
Isoptin SR
Point de fusion
< 25 oC
Isoptin SR
H2O Solubilite
4,47 mg / L
Isoptin SR
Etat
Liquid
Isoptin SR
LogP
5.931
Isoptin SR
Formes pharmaceutiques
Capsule (libération prolongée); liquide; Solution; Tablet; Tablet (libération prolongée)
Isoptin SR
Indication
Pour le traitement de l'hypertension et l'angine.
Isoptin SR
Pharmacologie
Vérapamil, un anti-arythmique de classe IV agent, est utilisé comme un blocage des canaux calciques (BCC) agent pour le traitement de l'angine, l'hypertension, et pour tachyarythmies supraventriculaires.
Isoptin SR
Absorption
90%
Isoptin SR
Toxicite
DL50 = 8 mg / kg (iv chez la souris)
Isoptin SR
Information pour les patients
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Isoptin SR
Organismes affectes
Les humains et autres mammifères