Zocord
Zocord Brand names, Zocord Analogs
Zocord Brand Names Mixture
- No information avaliable
Zocord Chemical_Formula
C25H38O5
Zocord RX_link
http://www.rxlist.com/cgi/generic/simva.htm
Zocord fda sheet
Zocord msds (material safety sheet)
Zocord Synthesis Reference
W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)
Zocord Molecular Weight
418.566 g/mol
Zocord Melting Point
135-138oC
Zocord H2O Solubility
0.76 mg/L
Zocord State
Solid
Zocord LogP
4.937
Zocord Dosage Forms
Tablet (oral)
Zocord Indication
For the treatment of hypercholesterolemia.
Zocord Pharmacology
Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.
Zocord Absorption
Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.
Zocord side effects and Toxicity
No information avaliable
Zocord Patient Information
Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.
Zocord Organisms Affected
Humans and other mammals
