Sinvacor
Sinvacor Brand names, Sinvacor Analogs
Sinvacor Brand Names Mixture
- No information avaliable
Sinvacor Chemical_Formula
C25H38O5
Sinvacor RX_link
http://www.rxlist.com/cgi/generic/simva.htm
Sinvacor fda sheet
Sinvacor msds (material safety sheet)
Sinvacor Synthesis Reference
W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)
Sinvacor Molecular Weight
418.566 g/mol
Sinvacor Melting Point
135-138oC
Sinvacor H2O Solubility
0.76 mg/L
Sinvacor State
Solid
Sinvacor LogP
4.937
Sinvacor Dosage Forms
Tablet (oral)
Sinvacor Indication
For the treatment of hypercholesterolemia.
Sinvacor Pharmacology
Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.
Sinvacor Absorption
Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.
Sinvacor side effects and Toxicity
No information avaliable
Sinvacor Patient Information
Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.
Sinvacor Organisms Affected
Humans and other mammals
