Vasotenal
Vasotenal Brand names, Vasotenal Analogs
Vasotenal Brand Names Mixture
- No information avaliable
Vasotenal Chemical_Formula
C25H38O5
Vasotenal RX_link
http://www.rxlist.com/cgi/generic/simva.htm
Vasotenal fda sheet
Vasotenal msds (material safety sheet)
Vasotenal Synthesis Reference
W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)
Vasotenal Molecular Weight
418.566 g/mol
Vasotenal Melting Point
135-138oC
Vasotenal H2O Solubility
0.76 mg/L
Vasotenal State
Solid
Vasotenal LogP
4.937
Vasotenal Dosage Forms
Tablet (oral)
Vasotenal Indication
For the treatment of hypercholesterolemia.
Vasotenal Pharmacology
Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.
Vasotenal Absorption
Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.
Vasotenal side effects and Toxicity
No information avaliable
Vasotenal Patient Information
Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.
Vasotenal Organisms Affected
Humans and other mammals
