Lipex
Lipex Brand names, Lipex Analogs
Lipex Brand Names Mixture
- No information avaliable
Lipex Chemical_Formula
C25H38O5
Lipex RX_link
http://www.rxlist.com/cgi/generic/simva.htm
Lipex fda sheet
Lipex msds (material safety sheet)
Lipex Synthesis Reference
W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)
Lipex Molecular Weight
418.566 g/mol
Lipex Melting Point
135-138oC
Lipex H2O Solubility
0.76 mg/L
Lipex State
Solid
Lipex LogP
4.937
Lipex Dosage Forms
Tablet (oral)
Lipex Indication
For the treatment of hypercholesterolemia.
Lipex Pharmacology
Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.
Lipex Absorption
Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.
Lipex side effects and Toxicity
No information avaliable
Lipex Patient Information
Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.
Lipex Organisms Affected
Humans and other mammals
