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Coledis Brand names, Coledis Analogs

Coledis Brand Names Mixture

  • No information avaliable

Coledis Chemical_Formula


Coledis RX_link

Coledis fda sheet

Coledis FDA

Coledis msds (material safety sheet)

Coledis Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Coledis Molecular Weight

418.566 g/mol

Coledis Melting Point


Coledis H2O Solubility

0.76 mg/L

Coledis State


Coledis LogP


Coledis Dosage Forms

Tablet (oral)

Coledis Indication

For the treatment of hypercholesterolemia.

Coledis Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Coledis Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Coledis side effects and Toxicity

No information avaliable

Coledis Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Coledis Organisms Affected

Humans and other mammals