Rendapid
Rendapid Brand names, Rendapid Analogs
Rendapid Brand Names Mixture
- No information avaliable
Rendapid Chemical_Formula
C25H38O5
Rendapid RX_link
http://www.rxlist.com/cgi/generic/simva.htm
Rendapid fda sheet
Rendapid msds (material safety sheet)
Rendapid Synthesis Reference
W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)
Rendapid Molecular Weight
418.566 g/mol
Rendapid Melting Point
135-138oC
Rendapid H2O Solubility
0.76 mg/L
Rendapid State
Solid
Rendapid LogP
4.937
Rendapid Dosage Forms
Tablet (oral)
Rendapid Indication
For the treatment of hypercholesterolemia.
Rendapid Pharmacology
Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.
Rendapid Absorption
Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.
Rendapid side effects and Toxicity
No information avaliable
Rendapid Patient Information
Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.
Rendapid Organisms Affected
Humans and other mammals
