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Colemin Brand names, Colemin Analogs

Colemin Brand Names Mixture

  • No information avaliable

Colemin Chemical_Formula


Colemin RX_link

Colemin fda sheet

Colemin FDA

Colemin msds (material safety sheet)

Colemin Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Colemin Molecular Weight

418.566 g/mol

Colemin Melting Point


Colemin H2O Solubility

0.76 mg/L

Colemin State


Colemin LogP


Colemin Dosage Forms

Tablet (oral)

Colemin Indication

For the treatment of hypercholesterolemia.

Colemin Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Colemin Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Colemin side effects and Toxicity

No information avaliable

Colemin Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Colemin Organisms Affected

Humans and other mammals