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Denan Brand names, Denan Analogs

Denan Brand Names Mixture

  • No information avaliable

Denan Chemical_Formula


Denan RX_link

Denan fda sheet

Denan FDA

Denan msds (material safety sheet)

Denan Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Denan Molecular Weight

418.566 g/mol

Denan Melting Point


Denan H2O Solubility

0.76 mg/L

Denan State


Denan LogP


Denan Dosage Forms

Tablet (oral)

Denan Indication

For the treatment of hypercholesterolemia.

Denan Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Denan Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Denan side effects and Toxicity

No information avaliable

Denan Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Denan Organisms Affected

Humans and other mammals