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Lodales Brand names, Lodales Analogs

Lodales Brand Names Mixture

  • No information avaliable

Lodales Chemical_Formula


Lodales RX_link


Lodales fda sheet

Lodales FDA

Lodales msds (material safety sheet)

Lodales Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Lodales Molecular Weight

418.566 g/mol

Lodales Melting Point


Lodales H2O Solubility

0.76 mg/L

Lodales State


Lodales LogP


Lodales Dosage Forms

Tablet (oral)

Lodales Indication

For the treatment of hypercholesterolemia.

Lodales Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Lodales Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Lodales side effects and Toxicity

No information avaliable

Lodales Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Lodales Organisms Affected

Humans and other mammals