Zocor
Zocor Brand names, Zocor Analogs
Zocor Brand Names Mixture
- No information avaliable
Zocor Chemical_Formula
C25H38O5
Zocor RX_link
http://www.rxlist.com/cgi/generic/simva.htm
Zocor fda sheet
Zocor msds (material safety sheet)
Zocor Synthesis Reference
W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)
Zocor Molecular Weight
418.566 g/mol
Zocor Melting Point
135-138oC
Zocor H2O Solubility
0.76 mg/L
Zocor State
Solid
Zocor LogP
4.937
Zocor Dosage Forms
Tablet (oral)
Zocor Indication
For the treatment of hypercholesterolemia.
Zocor Pharmacology
Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.
Zocor Absorption
Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.
Zocor side effects and Toxicity
No information avaliable
Zocor Patient Information
Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.
Zocor Organisms Affected
Humans and other mammals
