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Nivelipol Brand names, Nivelipol Analogs

Nivelipol Brand Names Mixture

  • No information avaliable

Nivelipol Chemical_Formula


Nivelipol RX_link

Nivelipol fda sheet

Nivelipol FDA

Nivelipol msds (material safety sheet)

Nivelipol Synthesis Reference

W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)

Nivelipol Molecular Weight

418.566 g/mol

Nivelipol Melting Point


Nivelipol H2O Solubility

0.76 mg/L

Nivelipol State


Nivelipol LogP


Nivelipol Dosage Forms

Tablet (oral)

Nivelipol Indication

For the treatment of hypercholesterolemia.

Nivelipol Pharmacology

Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.

Nivelipol Absorption

Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.

Nivelipol side effects and Toxicity

No information avaliable

Nivelipol Patient Information

Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.

Nivelipol Organisms Affected

Humans and other mammals