Ulcofalk
Brand names,
Ulcofalk
Analogs
Ulcofalk
Brand Names Mixture
Ulcofalk
Chemical_Formula
C10H16N6S
Ulcofalk
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Ulcofalk
fda sheet
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msds (material safety sheet)
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Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Ulcofalk
Molecular Weight
252.34 g/mol
Ulcofalk
Melting Point
142 oC
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H2O Solubility
0.5 g/100 mL
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State
Solid
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LogP
0.879
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Dosage Forms
Tablets; Oral solution
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Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Ulcofalk
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Ulcofalk
Absorption
Rapid 60-70%
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side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
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Patient Information
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Organisms Affected
Humans and other mammals