Tagamet
Tagamet Brand names, Tagamet Analogs
Tagamet Brand Names Mixture
- No information avaliable
Tagamet Chemical_Formula
C10H16N6S
Tagamet RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Tagamet fda sheet
Tagamet msds (material safety sheet)
Tagamet Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Tagamet Molecular Weight
252.34 g/mol
Tagamet Melting Point
142 oC
Tagamet H2O Solubility
0.5 g/100 mL
Tagamet State
Solid
Tagamet LogP
0.879
Tagamet Dosage Forms
Tablets; Oral solution
Tagamet Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Tagamet Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Tagamet Absorption
Rapid 60-70%
Tagamet side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Tagamet Patient Information
Tagamet Organisms Affected
Humans and other mammals
