Edalene
Brand names,
Edalene
Analogs
Edalene
Brand Names Mixture
Edalene
Chemical_Formula
C10H16N6S
Edalene
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Edalene
fda sheet
Edalene
msds (material safety sheet)
Edalene
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Edalene
Molecular Weight
252.34 g/mol
Edalene
Melting Point
142 oC
Edalene
H2O Solubility
0.5 g/100 mL
Edalene
State
Solid
Edalene
LogP
0.879
Edalene
Dosage Forms
Tablets; Oral solution
Edalene
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Edalene
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Edalene
Absorption
Rapid 60-70%
Edalene
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Edalene
Patient Information
Edalene
Organisms Affected
Humans and other mammals