Eureceptor
Brand names,
Eureceptor
Analogs
Eureceptor
Brand Names Mixture
Eureceptor
Chemical_Formula
C10H16N6S
Eureceptor
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Eureceptor
fda sheet
Eureceptor
msds (material safety sheet)
Eureceptor
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Eureceptor
Molecular Weight
252.34 g/mol
Eureceptor
Melting Point
142 oC
Eureceptor
H2O Solubility
0.5 g/100 mL
Eureceptor
State
Solid
Eureceptor
LogP
0.879
Eureceptor
Dosage Forms
Tablets; Oral solution
Eureceptor
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Eureceptor
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Eureceptor
Absorption
Rapid 60-70%
Eureceptor
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Eureceptor
Patient Information
Eureceptor
Organisms Affected
Humans and other mammals