Cimal
Cimal Brand names, Cimal Analogs
Cimal Brand Names Mixture
- No information avaliable
Cimal Chemical_Formula
C10H16N6S
Cimal RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Cimal fda sheet
Cimal msds (material safety sheet)
Cimal Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Cimal Molecular Weight
252.34 g/mol
Cimal Melting Point
142 oC
Cimal H2O Solubility
0.5 g/100 mL
Cimal State
Solid
Cimal LogP
0.879
Cimal Dosage Forms
Tablets; Oral solution
Cimal Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Cimal Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Cimal Absorption
Rapid 60-70%
Cimal side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Cimal Patient Information
Cimal Organisms Affected
Humans and other mammals
