Ulcimet
Brand names,
Ulcimet
Analogs
Ulcimet
Brand Names Mixture
Ulcimet
Chemical_Formula
C10H16N6S
Ulcimet
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Ulcimet
fda sheet
Ulcimet
msds (material safety sheet)
Ulcimet
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Ulcimet
Molecular Weight
252.34 g/mol
Ulcimet
Melting Point
142 oC
Ulcimet
H2O Solubility
0.5 g/100 mL
Ulcimet
State
Solid
Ulcimet
LogP
0.879
Ulcimet
Dosage Forms
Tablets; Oral solution
Ulcimet
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Ulcimet
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Ulcimet
Absorption
Rapid 60-70%
Ulcimet
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Ulcimet
Patient Information
Ulcimet
Organisms Affected
Humans and other mammals