Cimetum
Brand names,
Cimetum
Analogs
Cimetum
Brand Names Mixture
Cimetum
Chemical_Formula
C10H16N6S
Cimetum
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Cimetum
fda sheet
Cimetum
msds (material safety sheet)
Cimetum
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Cimetum
Molecular Weight
252.34 g/mol
Cimetum
Melting Point
142 oC
Cimetum
H2O Solubility
0.5 g/100 mL
Cimetum
State
Solid
Cimetum
LogP
0.879
Cimetum
Dosage Forms
Tablets; Oral solution
Cimetum
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Cimetum
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Cimetum
Absorption
Rapid 60-70%
Cimetum
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Cimetum
Patient Information
Cimetum
Organisms Affected
Humans and other mammals