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Tratul Brand names, Tratul Analogs

Tratul Brand Names Mixture

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Tratul Chemical_Formula


Tratul RX_link

Tratul fda sheet

Tratul FDA

Tratul msds (material safety sheet)

Tratul Synthesis Reference

G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)

Tratul Molecular Weight

252.34 g/mol

Tratul Melting Point

142 oC

Tratul H2O Solubility

0.5 g/100 mL

Tratul State


Tratul LogP


Tratul Dosage Forms

Tablets; Oral solution

Tratul Indication

For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion

Tratul Pharmacology

Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.

Tratul Absorption

Rapid 60-70%

Tratul side effects and Toxicity

nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.

Tratul Patient Information

Tratul Organisms Affected

Humans and other mammals