Dyspamet
Brand names,
Dyspamet
Analogs
Dyspamet
Brand Names Mixture
Dyspamet
Chemical_Formula
C10H16N6S
Dyspamet
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Dyspamet
fda sheet
Dyspamet
msds (material safety sheet)
Dyspamet
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Dyspamet
Molecular Weight
252.34 g/mol
Dyspamet
Melting Point
142 oC
Dyspamet
H2O Solubility
0.5 g/100 mL
Dyspamet
State
Solid
Dyspamet
LogP
0.879
Dyspamet
Dosage Forms
Tablets; Oral solution
Dyspamet
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Dyspamet
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Dyspamet
Absorption
Rapid 60-70%
Dyspamet
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Dyspamet
Patient Information
Dyspamet
Organisms Affected
Humans and other mammals