Peptol
Brand names,
Peptol
Analogs
Peptol
Brand Names Mixture
Peptol
Chemical_Formula
C10H16N6S
Peptol
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Peptol
fda sheet
Peptol
msds (material safety sheet)
Peptol
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Peptol
Molecular Weight
252.34 g/mol
Peptol
Melting Point
142 oC
Peptol
H2O Solubility
0.5 g/100 mL
Peptol
State
Solid
Peptol
LogP
0.879
Peptol
Dosage Forms
Tablets; Oral solution
Peptol
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Peptol
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Peptol
Absorption
Rapid 60-70%
Peptol
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Peptol
Patient Information
Peptol
Organisms Affected
Humans and other mammals