Cimetidine Hcl
Cimetidine Hcl Brand names, Cimetidine Hcl Analogs
Cimetidine Hcl Brand Names Mixture
- No information avaliable
Cimetidine Hcl Chemical_Formula
C10H16N6S
Cimetidine Hcl RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Cimetidine Hcl fda sheet
Cimetidine Hcl msds (material safety sheet)
Cimetidine Hcl Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Cimetidine Hcl Molecular Weight
252.34 g/mol
Cimetidine Hcl Melting Point
142 oC
Cimetidine Hcl H2O Solubility
0.5 g/100 mL
Cimetidine Hcl State
Solid
Cimetidine Hcl LogP
0.879
Cimetidine Hcl Dosage Forms
Tablets; Oral solution
Cimetidine Hcl Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Cimetidine Hcl Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Cimetidine Hcl Absorption
Rapid 60-70%
Cimetidine Hcl side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Cimetidine Hcl Patient Information
Cimetidine Hcl Organisms Affected
Humans and other mammals
