Ulcedine
Brand names,
Ulcedine
Analogs
Ulcedine
Brand Names Mixture
Ulcedine
Chemical_Formula
C10H16N6S
Ulcedine
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Ulcedine
fda sheet
Ulcedine
msds (material safety sheet)
Ulcedine
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Ulcedine
Molecular Weight
252.34 g/mol
Ulcedine
Melting Point
142 oC
Ulcedine
H2O Solubility
0.5 g/100 mL
Ulcedine
State
Solid
Ulcedine
LogP
0.879
Ulcedine
Dosage Forms
Tablets; Oral solution
Ulcedine
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Ulcedine
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Ulcedine
Absorption
Rapid 60-70%
Ulcedine
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Ulcedine
Patient Information
Ulcedine
Organisms Affected
Humans and other mammals