Acinil
Acinil Brand names, Acinil Analogs
Acinil Brand Names Mixture
- No information avaliable
Acinil Chemical_Formula
C10H16N6S
Acinil RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Acinil fda sheet
Acinil msds (material safety sheet)
Acinil Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Acinil Molecular Weight
252.34 g/mol
Acinil Melting Point
142 oC
Acinil H2O Solubility
0.5 g/100 mL
Acinil State
Solid
Acinil LogP
0.879
Acinil Dosage Forms
Tablets; Oral solution
Acinil Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Acinil Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Acinil Absorption
Rapid 60-70%
Acinil side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Acinil Patient Information
Acinil Organisms Affected
Humans and other mammals
