Acibilin
Brand names,
Acibilin
Analogs
Acibilin
Brand Names Mixture
Acibilin
Chemical_Formula
C10H16N6S
Acibilin
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Acibilin
fda sheet
Acibilin
msds (material safety sheet)
Acibilin
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Acibilin
Molecular Weight
252.34 g/mol
Acibilin
Melting Point
142 oC
Acibilin
H2O Solubility
0.5 g/100 mL
Acibilin
State
Solid
Acibilin
LogP
0.879
Acibilin
Dosage Forms
Tablets; Oral solution
Acibilin
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Acibilin
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Acibilin
Absorption
Rapid 60-70%
Acibilin
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Acibilin
Patient Information
Acibilin
Organisms Affected
Humans and other mammals