Tagamet Hb
Brand names,
Tagamet Hb
Analogs
Tagamet Hb
Brand Names Mixture
Tagamet Hb
Chemical_Formula
C10H16N6S
Tagamet Hb
RX_link
http://www.rxlist.com/cgi/generic/cimet.htm
Tagamet Hb
fda sheet
Tagamet Hb
msds (material safety sheet)
Tagamet Hb
Synthesis Reference
G. J. Durant et al.; U.S. Pat. 3,950,333 (1976)
Tagamet Hb
Molecular Weight
252.34 g/mol
Tagamet Hb
Melting Point
142 oC
Tagamet Hb
H2O Solubility
0.5 g/100 mL
Tagamet Hb
State
Solid
Tagamet Hb
LogP
0.879
Tagamet Hb
Dosage Forms
Tablets; Oral solution
Tagamet Hb
Indication
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion
Tagamet Hb
Pharmacology
Cimetidine is a histamine H2-receptor antagonist. It reduces basal and nocturnal gastric acid secretion and a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli including food, caffeine, insulin, betazole, or pentagastrin. It is used to treat gastrointestinal disorders such as gastric or duodenal ulcer, gastroesophageal reflux disease, and pathological hypersecretory conditions. Cimetidine inhibits many of the isoenzymes of the hepatic CYP450 enzyme system. Other actions of Cimetidine include an increase in gastric bacterial flora such as nitrate-reducing organisms.
Tagamet Hb
Absorption
Rapid 60-70%
Tagamet Hb
side effects and Toxicity
nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Tagamet Hb
Patient Information
Tagamet Hb
Organisms Affected
Humans and other mammals