Sesaval
Brand names,
Sesaval
Analogs
Sesaval
Brand Names Mixture
Sesaval
Chemical_Formula
C19H21N
Sesaval
RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Sesaval
fda sheet
Sesaval
msds (material safety sheet)
Sesaval
Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Sesaval
Molecular Weight
263.377 g/mol
Sesaval
Melting Point
213-215oC
Sesaval
H2O Solubility
No information avaliable
Sesaval
State
Solid
Sesaval
LogP
4.298
Sesaval
Dosage Forms
Capsules
Sesaval
Indication
For the treatment of depression.
Sesaval
Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Sesaval
Absorption
Well absorbed from the GI tract.
Sesaval
side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Sesaval
Patient Information
Sesaval
Organisms Affected
Humans and other mammals