Nortryptiline
Brand names,
Nortryptiline
Analogs
Nortryptiline
Brand Names Mixture
Nortryptiline
Chemical_Formula
C19H21N
Nortryptiline
RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Nortryptiline
fda sheet
Nortryptiline
msds (material safety sheet)
Nortryptiline
Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Nortryptiline
Molecular Weight
263.377 g/mol
Nortryptiline
Melting Point
213-215oC
Nortryptiline
H2O Solubility
No information avaliable
Nortryptiline
State
Solid
Nortryptiline
LogP
4.298
Nortryptiline
Dosage Forms
Capsules
Nortryptiline
Indication
For the treatment of depression.
Nortryptiline
Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Nortryptiline
Absorption
Well absorbed from the GI tract.
Nortryptiline
side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Nortryptiline
Patient Information
Nortryptiline
Organisms Affected
Humans and other mammals