Demethylamitriptylene
Demethylamitriptylene Brand names, Demethylamitriptylene Analogs
- AVENTYL HCL
- Acetexa
- Allegron
- Altilev
- Amitryptyline, Demethyl-
- Ateben
- Avantyl
- Aventyl
- Demethylamitriptylene
- Demethylamitriptyline
- Demethylamitryptyline
- Desitriptilina
- Desmethylamitriptyline
- Lumbeck
- Noramitriptyline
- Noritren
- Nortrilen
- Nortriptyline Hcl
- Nortryptiline
- Norzepine
- PAMELOR
- Psychostyl
- Sensaval
- Sensival Ventyl
- Sesaval
- Vividyl
Demethylamitriptylene Brand Names Mixture
- No information avaliable
Demethylamitriptylene Chemical_Formula
C19H21N
Demethylamitriptylene RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Demethylamitriptylene fda sheet
Demethylamitriptylene msds (material safety sheet)
Demethylamitriptylene Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Demethylamitriptylene Molecular Weight
263.377 g/mol
Demethylamitriptylene Melting Point
213-215oC
Demethylamitriptylene H2O Solubility
No information avaliable
Demethylamitriptylene State
Solid
Demethylamitriptylene LogP
4.298
Demethylamitriptylene Dosage Forms
Capsules
Demethylamitriptylene Indication
For the treatment of depression.
Demethylamitriptylene Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Demethylamitriptylene Absorption
Well absorbed from the GI tract.
Demethylamitriptylene side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Demethylamitriptylene Patient Information
Demethylamitriptylene Organisms Affected
Humans and other mammals
