Desmethylamitriptyline
Desmethylamitriptyline Brand names, Desmethylamitriptyline Analogs
- AVENTYL HCL
- Acetexa
- Allegron
- Altilev
- Amitryptyline, Demethyl-
- Ateben
- Avantyl
- Aventyl
- Demethylamitriptylene
- Demethylamitriptyline
- Demethylamitryptyline
- Desitriptilina
- Desmethylamitriptyline
- Lumbeck
- Noramitriptyline
- Noritren
- Nortrilen
- Nortriptyline Hcl
- Nortryptiline
- Norzepine
- PAMELOR
- Psychostyl
- Sensaval
- Sensival Ventyl
- Sesaval
- Vividyl
Desmethylamitriptyline Brand Names Mixture
- No information avaliable
Desmethylamitriptyline Chemical_Formula
C19H21N
Desmethylamitriptyline RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Desmethylamitriptyline fda sheet
Desmethylamitriptyline msds (material safety sheet)
Desmethylamitriptyline Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Desmethylamitriptyline Molecular Weight
263.377 g/mol
Desmethylamitriptyline Melting Point
213-215oC
Desmethylamitriptyline H2O Solubility
No information avaliable
Desmethylamitriptyline State
Solid
Desmethylamitriptyline LogP
4.298
Desmethylamitriptyline Dosage Forms
Capsules
Desmethylamitriptyline Indication
For the treatment of depression.
Desmethylamitriptyline Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Desmethylamitriptyline Absorption
Well absorbed from the GI tract.
Desmethylamitriptyline side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Desmethylamitriptyline Patient Information
Desmethylamitriptyline Organisms Affected
Humans and other mammals
