Desitriptilina
Brand names,
Desitriptilina
Analogs
Desitriptilina
Brand Names Mixture
Desitriptilina
Chemical_Formula
C19H21N
Desitriptilina
RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Desitriptilina
fda sheet
Desitriptilina
msds (material safety sheet)
Desitriptilina
Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Desitriptilina
Molecular Weight
263.377 g/mol
Desitriptilina
Melting Point
213-215oC
Desitriptilina
H2O Solubility
No information avaliable
Desitriptilina
State
Solid
Desitriptilina
LogP
4.298
Desitriptilina
Dosage Forms
Capsules
Desitriptilina
Indication
For the treatment of depression.
Desitriptilina
Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Desitriptilina
Absorption
Well absorbed from the GI tract.
Desitriptilina
side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Desitriptilina
Patient Information
Desitriptilina
Organisms Affected
Humans and other mammals