Sensaval
Brand names,
Sensaval
Analogs
Sensaval
Brand Names Mixture
Sensaval
Chemical_Formula
C19H21N
Sensaval
RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Sensaval
fda sheet
Sensaval
msds (material safety sheet)
Sensaval
Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Sensaval
Molecular Weight
263.377 g/mol
Sensaval
Melting Point
213-215oC
Sensaval
H2O Solubility
No information avaliable
Sensaval
State
Solid
Sensaval
LogP
4.298
Sensaval
Dosage Forms
Capsules
Sensaval
Indication
For the treatment of depression.
Sensaval
Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Sensaval
Absorption
Well absorbed from the GI tract.
Sensaval
side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Sensaval
Patient Information
Sensaval
Organisms Affected
Humans and other mammals