Allegron
Brand names,
Allegron
Analogs
Allegron
Brand Names Mixture
Allegron
Chemical_Formula
C19H21N
Allegron
RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Allegron
fda sheet
Allegron
msds (material safety sheet)
Allegron
Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Allegron
Molecular Weight
263.377 g/mol
Allegron
Melting Point
213-215oC
Allegron
H2O Solubility
No information avaliable
Allegron
State
Solid
Allegron
LogP
4.298
Allegron
Dosage Forms
Capsules
Allegron
Indication
For the treatment of depression.
Allegron
Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Allegron
Absorption
Well absorbed from the GI tract.
Allegron
side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Allegron
Patient Information
Allegron
Organisms Affected
Humans and other mammals