Noramitriptyline
Brand names,
Noramitriptyline
Analogs
Noramitriptyline
Brand Names Mixture
Noramitriptyline
Chemical_Formula
C19H21N
Noramitriptyline
RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Noramitriptyline
fda sheet
Noramitriptyline
msds (material safety sheet)
Noramitriptyline
Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Noramitriptyline
Molecular Weight
263.377 g/mol
Noramitriptyline
Melting Point
213-215oC
Noramitriptyline
H2O Solubility
No information avaliable
Noramitriptyline
State
Solid
Noramitriptyline
LogP
4.298
Noramitriptyline
Dosage Forms
Capsules
Noramitriptyline
Indication
For the treatment of depression.
Noramitriptyline
Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Noramitriptyline
Absorption
Well absorbed from the GI tract.
Noramitriptyline
side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Noramitriptyline
Patient Information
Noramitriptyline
Organisms Affected
Humans and other mammals