Acetexa
Brand names,
Acetexa
Analogs
Acetexa
Brand Names Mixture
Acetexa
Chemical_Formula
C19H21N
Acetexa
RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Acetexa
fda sheet
Acetexa
msds (material safety sheet)
Acetexa
Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Acetexa
Molecular Weight
263.377 g/mol
Acetexa
Melting Point
213-215oC
Acetexa
H2O Solubility
No information avaliable
Acetexa
State
Solid
Acetexa
LogP
4.298
Acetexa
Dosage Forms
Capsules
Acetexa
Indication
For the treatment of depression.
Acetexa
Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Acetexa
Absorption
Well absorbed from the GI tract.
Acetexa
side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Acetexa
Patient Information
Acetexa
Organisms Affected
Humans and other mammals