Psychostyl
Brand names,
Psychostyl
Analogs
Psychostyl
Brand Names Mixture
Psychostyl
Chemical_Formula
C19H21N
Psychostyl
RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Psychostyl
fda sheet
Psychostyl
msds (material safety sheet)
Psychostyl
Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Psychostyl
Molecular Weight
263.377 g/mol
Psychostyl
Melting Point
213-215oC
Psychostyl
H2O Solubility
No information avaliable
Psychostyl
State
Solid
Psychostyl
LogP
4.298
Psychostyl
Dosage Forms
Capsules
Psychostyl
Indication
For the treatment of depression.
Psychostyl
Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Psychostyl
Absorption
Well absorbed from the GI tract.
Psychostyl
side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Psychostyl
Patient Information
Psychostyl
Organisms Affected
Humans and other mammals