Demethylamitriptyline
Demethylamitriptyline Brand names, Demethylamitriptyline Analogs
- AVENTYL HCL
- Acetexa
- Allegron
- Altilev
- Amitryptyline, Demethyl-
- Ateben
- Avantyl
- Aventyl
- Demethylamitriptylene
- Demethylamitriptyline
- Demethylamitryptyline
- Desitriptilina
- Desmethylamitriptyline
- Lumbeck
- Noramitriptyline
- Noritren
- Nortrilen
- Nortriptyline Hcl
- Nortryptiline
- Norzepine
- PAMELOR
- Psychostyl
- Sensaval
- Sensival Ventyl
- Sesaval
- Vividyl
Demethylamitriptyline Brand Names Mixture
- No information avaliable
Demethylamitriptyline Chemical_Formula
C19H21N
Demethylamitriptyline RX_link
http://www.rxlist.com/cgi/generic/nortrip.htm
Demethylamitriptyline fda sheet
Demethylamitriptyline msds (material safety sheet)
Demethylamitriptyline Synthesis Reference
E. I. Engelhardt, U.S. Pat. 3,922,305 (1975)
Demethylamitriptyline Molecular Weight
263.377 g/mol
Demethylamitriptyline Melting Point
213-215oC
Demethylamitriptyline H2O Solubility
No information avaliable
Demethylamitriptyline State
Solid
Demethylamitriptyline LogP
4.298
Demethylamitriptyline Dosage Forms
Capsules
Demethylamitriptyline Indication
For the treatment of depression.
Demethylamitriptyline Pharmacology
Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.
Demethylamitriptyline Absorption
Well absorbed from the GI tract.
Demethylamitriptyline side effects and Toxicity
Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. LD50=mg/kg(orally in rat)
Demethylamitriptyline Patient Information
Demethylamitriptyline Organisms Affected
Humans and other mammals
