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ROC Brand names, ROC Analogs

ROC Brand Names Mixture

  • No information avaliable

ROC Chemical_Formula

C17H21NO4

ROC RX_link

http://www.rxlist.com/cgi/generic/cocaine.htm

ROC fda sheet

ROC msds (material safety sheet)

ROC MSDS

ROC Synthesis Reference

No information avaliable

ROC Molecular Weight

303.353 g/mol

ROC Melting Point

195 oC

ROC H2O Solubility

1800 mg/L

ROC State

Solid

ROC LogP

2.393

ROC Dosage Forms

Liquid

ROC Indication

For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.

ROC Pharmacology

Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.

ROC Absorption

Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.

ROC side effects and Toxicity

Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg

ROC Patient Information

No information avaliable

ROC Organisms Affected

Humans and other mammals