Cabello
Brand names,
Cabello
Analogs
Cabello
Brand Names Mixture
Cabello
Chemical_Formula
C17H21NO4
Cabello
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Cabello
fda sheet
Cabello
msds (material safety sheet)
Cabello
Synthesis Reference
No information avaliable
Cabello
Molecular Weight
303.353 g/mol
Cabello
Melting Point
195 oC
Cabello
H2O Solubility
1800 mg/L
Cabello
State
Solid
Cabello
LogP
2.393
Cabello
Dosage Forms
Liquid
Cabello
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Cabello
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Cabello
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Cabello
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Cabello
Patient Information
No information avaliable
Cabello
Organisms Affected
Humans and other mammals