Erytroxylin
Brand names,
Erytroxylin
Analogs
Erytroxylin
Brand Names Mixture
Erytroxylin
Chemical_Formula
C17H21NO4
Erytroxylin
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Erytroxylin
fda sheet
Erytroxylin
msds (material safety sheet)
Erytroxylin
Synthesis Reference
No information avaliable
Erytroxylin
Molecular Weight
303.353 g/mol
Erytroxylin
Melting Point
195 oC
Erytroxylin
H2O Solubility
1800 mg/L
Erytroxylin
State
Solid
Erytroxylin
LogP
2.393
Erytroxylin
Dosage Forms
Liquid
Erytroxylin
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Erytroxylin
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Erytroxylin
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Erytroxylin
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Erytroxylin
Patient Information
No information avaliable
Erytroxylin
Organisms Affected
Humans and other mammals