Burese
Brand names,
Burese
Analogs
Burese
Brand Names Mixture
Burese
Chemical_Formula
C17H21NO4
Burese
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
303.353 g/mol
Burese
Melting Point
195 oC
Burese
H2O Solubility
1800 mg/L
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State
Solid
Burese
LogP
2.393
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Dosage Forms
Liquid
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Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Burese
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Burese
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
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side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
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Patient Information
No information avaliable
Burese
Organisms Affected
Humans and other mammals