Kokayeen
Brand names,
Kokayeen
Analogs
Kokayeen
Brand Names Mixture
Kokayeen
Chemical_Formula
C17H21NO4
Kokayeen
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Kokayeen
fda sheet
Kokayeen
msds (material safety sheet)
Kokayeen
Synthesis Reference
No information avaliable
Kokayeen
Molecular Weight
303.353 g/mol
Kokayeen
Melting Point
195 oC
Kokayeen
H2O Solubility
1800 mg/L
Kokayeen
State
Solid
Kokayeen
LogP
2.393
Kokayeen
Dosage Forms
Liquid
Kokayeen
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Kokayeen
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Kokayeen
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Kokayeen
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Kokayeen
Patient Information
No information avaliable
Kokayeen
Organisms Affected
Humans and other mammals